Friday, June 7, 2013

Finding sequences in other Rhododendron species

When you're interested in a genomic region, you can make use of RAD-seq data to investigate polymorphisms across Rhododendron. Instead of doing PCR and sequencing, you can find the sequence from genomic regions near a PstI restriction site (CTGCAG).

Data is loaded on the iMacs, see below for instructions. This will be similar to the RNA-seq from last week.

Open a Terminal window

cd RAD_seq

Add your sequence of interest in fasta format to input.fasta, then:

./blastn -query input.fasta -db all96.trimmed.spnames.fa -task blastn -outfmt 7


To get the sequence of the blast hit:

grep -A1 [SEQUENCENAME] all96.trimmed.spnames.fa

It's also possible to get several to many sequences at a time, let me know if you're interested in that.

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